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Long-term results of ring-pattern local corneal cross-linking for progressive keratoconus treatment

Poster Details

First Author: N.Anisimova RUSSIA

Co Author(s):    S. Anisimov   A. Zemskaya   S. Anisimova              

Abstract Details

Purpose:

To report the long-term results of the ring-shape local corneal cross-linking

Setting:

Private Eye Center “Vostok-Prozrenie”, A. Yevdokimov Moscow Medical and Dental State University, Moscow, Russia

Methods:

From September 2014 to February 2017, 30 eyes (30 patients) with progressive keratoconus were treated with riboflavin ultraviolet A the ring-shape local corneal cross-linking. Stage 2 and 3 progressive keratoconus were included in the study. Patients with a minimum follow-up of 12 months were evaluated before and after surgery. Examinations comprised standard ophthalmological examination included uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), tomography (Orbscan IIz; Bausch & Lomb Inc., Rochester, New York, USA). Preoperatively minimal corneal thickness (CTmin) was 468±63 um, Kmax 49.0±5.7

Results:

Neither of the patients had a corneal haze of the central zone of the cornea within the 3 mm nor had progression of keratectasia. No change in CTmin was observed after the surgery in 6 and 12 months of follow-up and was  433±98 and 448±80um (p=0.09, Wilcoxon test), respectively. UCVA improved in 16 cases (53%) no change in 8 cases was recorded (27%), BCVA improved in 17 cases (57%) no change in 9 cases (30%). Delta Ker (max) was -0.13±0.79D (p=0.9, Wilcoxon test) when comparing preoperative data to data in 12 months follow-up.

Conclusions:

Ring-pattern local corneal cross-linking is an effective method in stabilizing the pathological process,  its functional and clinical postoperative results improved in cases of keratoconus progression. Further investigation will compare the Dresden protocol with the proposed technique and the sample size would be increased by the date of the presentation.

Financial Disclosure:

None

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