Posters

Visual and topographical outcomes following accelerated corneal cross-linking in progressive keratoconus

Poster Details

First Author: F.Akkan Aydogmus TURKEY

Co Author(s):    E. Karaca   D. Ozek   G. Celık   O. Evren Kemer           

Abstract Details

Purpose:

To evaluate changes in vision and the optical performance of the cornea in patients with keratoconus following treatment with accelerated corneal crosslinking (CXL)

Setting:

University of Health Sciences Ankara Numune Training and Research Hospital

Methods:

Sixty-two eyes of 40 keratoconus patients with a mean follow up of 12 months after CXL were included. Demographic characteristics, best corrected visual acuities (BCVA), follow-up time, simulated keratometry values (sim K), spherical equivalent (SE), root mean square higher order aberrations( RMS HOA) , RMS lower order aberrations  (RMS LOA),  RMS total, peak to wall, thinnest pachymetry and  pachymetry apex values before and after the treatment were reviewed retrospectively.  The patients were divided into two groups as those with sim K values below 50 D (Group 1, 36 patients) and above 50 D (Group 2, 26 patients).

Results:

The mean age of  Group 1 and Group 2 were 24,58 ± 5,35  and 24,54 ± 6,48 years, respectively. In group 1, the increase in BCVA was not significant (p=0,09) but the improvement in sim K (p=0,00) and SE (p=0,00) were significant. In group 2, mean BCVA showed improvement of three lines from LogMAR 0.78 ± 0.5 to LogMAR 0.48 ±0.48 (p=0,016). Also the mean sim K flattened by 1,3 D (p=0,016). SE decreased up (p=0,001) and the improvement in RMS HOA was significant (p=0,0047). In group 2, the change in BCVA was correlated with the change in RMS HOA.

Conclusions:

Accelerated CXL makes refractive correction in both low and high-grade keratoconus, but there is a greater reduction in high-order aberrations in high-grade keratoconus patients.

Financial Disclosure:

None