Posters
Efficiency of autologous blood vs fibrin glue in pterygium excision with conjunctival autograft technique
Poster Details
First Author: M.Uddaraju INDIA
Co Author(s):
Abstract Details
Purpose:
To assess the efficiency of securing conjunctival autograft using autologous blood at the surgical site, and to compare it with fibrin glue for graft adherence, recurrence, surgical time & cost effectiveness in pterygium surgery
Setting:
A single-centre, prospective, randomised controlled trial
Methods:
596 eyes of patients with primary pterygia who were advised pterygium excision with CAG. Enrolled participants were assigned to autologous blood group or fibrin glue group by randomisation. After excision of pterygium, they underwent CAG with autologous blood in Group I (302 eyes) and CAG with fibrin glue in Group II (322 eyes). During follow-up of 1 year, the eyes were assessed for graft adherence and recurrence. The average surgical time and cost involved for both the procedures were also compared.
Results:
596 eyes (Group I n=287, Group II n=309), on the first postoperative day, 18 eyes in Group I (6.2%) had total graft dislodgement requiring regrafting or reattachment with glue or sutures. In Group II also 4 eyes (1.3%) had graft dislodgement on the first postoperative day requiring regrafting with sutures. During the 1-year follow-up, 13 eyes in Group I (4.5%) and 8 eyes in Group II (2.5%) developed recurrence resulting in no statistical difference (p<0.05).
Conclusions:
Clinical outcomes of adherence of the graft with autologous blood in pterygium surgery is comparable with the fibrin glue technique in terms of long-term outcome and recurrence, suggesting the potential for autologous blood to replace fibrin glue in graft fixation. However the time taken for the procedure was relatively longer when compared to fibrin glue procedure. The autologous blood procedure was definitely more economical and relevant to our patient population from rural backgrounds.
Financial Disclosure:
None
