Posters

Neurotrophic keratopathy in Apert syndrome

Poster Details

First Author: R.Quintana Conte SPAIN

Co Author(s):                        

Abstract Details

Purpose:

To describe two cases diagnosed with Apert syndrome presenting neurotrophic keratopaty without corneal exposure and its therapeutic management with amniotic membrane transplantation.

Setting:

Hospital Clínic Barcelona. Universitat Barcelona.

Methods:

Two patients diagnosed with Apert syndrome are described, presenting with neurotrophic corneal ulcers, without accompanying inflammatory signs or corneal exposure. The lesions were located in the lower paracentral area and had a rounded shape, with no over-elevated edges or adjacent infiltration. The course, in both cases, males of 17 and 23 years, was indolent and did not improve with conventional treatment.

Results:

Treatment was initiated with artificial tears,occlusion, therapeutic contact lens and autologous serum. Due to the slow progression of the clinical picture with thinning of the cornea, we proceeded to perform amniotic membrane transplant in multilayer pattern, managing to solve the ulcer with little visual impact. The final visual acuity was 0.10 logMart in both cases.

Conclusions:

The corneal complications of Apert syndrome are usually by exposure, we must take into account Neurotrophic ulcer when there is no corneal exposure. The Amniotic membrane has shown its usefulness in these cases.

Financial Disclosure:

None