Posters

Outcomes of Descemet's membrane endothelial keratoplasty (DMEK) in patients with pseudophakic bullous keratopathy (PBK)

Poster Details

First Author: A.Kate INDIA

Co Author(s):    P. Vaddavalli   P. Gogri   A. Koul              

Abstract Details

Purpose:

DMEK is now one of the preferred procedures for managing cases with endothelial dysfunction. Review of literature shows various studies on outcomes of the procedure done in Fuch’s endothelial dystrophy, however there is lacunae with regard to outcomes specifically in patients with PBK. We report 54 cases and their outcomes where DMEK was done in these cases.

Setting:

Tertiary Eye Care Centre in India

Methods:

Retrospective review of all cases with PBK who underwent DMEK in the period between 2016-2018. The uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA) endothelial cell density measured preoperatively, 1 month postoperatively and at the last follow up after DMEK were recorded along with the outcomes in terms of the detachment rates and need of subsequent surgery.

Results:

Sixty eyes of 59 patients were included in the study. Preoperatively, the UCVA was -1.24±0.18 logMAR and BCVA was -1.5±0.41 logMAR, which improved to -0.72± 0.57 logMAR and -0.47±0.54 logMAR respectively, at the last follow-up visit. The difference between both the UCVA and BCVA preoperatively and at the last visit postoperatively was found to be statistically significant (p= 0.00001).  The mean endothelial cell density on specular microscopy was 1409.18± 388.79 at 3 months which dropped to 1389.26± 500.45 cells/ mm2 at the last visit (p= 0.44). Out of 60 eyes, nine (15%) eyes had detached lenticule postoperatively.

Conclusions:

Outcomes of DMEK surgery in cases of Pseudophakic bullous keratopathy are encouraging and therefore it remains a viable and preferred surgical procedure for these cases.

Financial Disclosure:

None