Posters

Evolution of corneal transplantations on sequelae of herpetic keratitis

Poster Details

First Author: P.Dubrulle FRANCE

Co Author(s):    E. Gabison   Y. Abdelmassih   C. Sitbon   D. Guindolet   I. Cochereau   M. Labetoulle     

Abstract Details

Purpose:

To evaluate the management and evolution of corneal transplant’s patients with a history of herpetic keratitis in the Rothschild Ophthalmological Foundation between 2011 and 2017

Setting:

Retrospective and mono-centric study, based on the collection of informatics data from patients transplanted to the Rothschild Ophthalmological Foundation between 2011 and 2017, with a history of herpetic keratitis and an antiviral prophylaxis.

Methods:

We collected for each patient the preoperative clinical data, as well as the percentage and timing of complications related to different types of corneal transplants and herpetic keratitis recurrences.

Results:

57 eyes were included: 25 PK, 7 DALK, 6 DSAEK, 19 DMEK. The final average postoperative decimal VA was 0.40+/-0.33; 0.31+/-0.28 for PK; 0.45+/-0.39 DALK; 0.53+/-0.35 DSAEK; 0.46+/-0.35 DMEK. The postoperative herpes recurrence rate was 33.3%; 36.0% KT; 28.6% DALK; 16.7% DSAEK; 36.8% DMEK. The postoperative endothelitis rate was 21.0%; 20.0% PK; 14.3% DALK; 16.7% DSAEK; 26.3% DMEK. The postoperative ulcer rate was 17.5%; 8.0% PK; 28.6% DALK; none DSAEK; 31.6% DMEK. The rejection rate was 29.8%; 40.0% PK; 14.3% DALK; none DSAEK; 31.6% DMEK. The postoperative failure rate was 26.2%; 16.0% PK; 28.6% DALK; 33.3% DSAEK; 36.8% DMEK.

Conclusions:

Corneal transplants are still and always an important recourse to blinding corneal herpetic pathologies. New corneal transplantion techniques promise better functional results, but do not prevent a high rate of postoperative complications. A good clinical analysis of preoperative risk factors, appropriate prophylaxis, close monitoring and anticipation of these complications is essential to maximize the benefits of these new surgeries.

Financial Disclosure:

None