Posters

Indications, clinical outcomes, and surgical techniques of corneal transplantation in an academic centre in Canada

Poster Details

First Author: Y.Chen CANADA

Co Author(s):    R. Tan   F. Mostofian   H. Nithianandan   S. Ziai   G. Mintsioulis   K. Baig     

Abstract Details

Purpose:

To analyze the changes in techniques, outcomes, complications and indications of cornea transplantation in a span of 8 years at a tertiary care center in North America.

Setting:

University of Ottawa Eye Institute, Ottawa, Canada.

Methods:

A retrospective chart review of all corneal transplantation at a Canadian academic hospital from 2008-2016 was completed. Number of corneal grafts for various keratoplasties, their surgical indications and complications were compared.  Procedures were classified as penetrating keratoplasty (PKP); Descemet’s Membrane Endothelial Keratoplasty (DMEK); Descemet's stripping automated endothelial keratoplasty (DSAEK) or ultra-thin DSAEK; or deep anterior lamellar keratoplasty (DALK).

Results:

A total of 883 corneal transplants were performed in 8 years. Of these, 371 were DSAEK (42%); 299 PKPs (33.3%); 159 DMEKs (18%); 37 DALKs (4.2%); and 17 ultra-thin DSAEKs (2%). The most common reason for transplantation was previously failed graft, 33% (290/883) of corneal transplants.  Corneal dystrophy, including Fuchs dystrophy, was the most common pathology requiring transplantation (236/883, 27%).  Overall graft survival rate was 75.5%; with the mean time to graft failure of 14.1 months. Elevated intraocular pressure was the most observed post-operative complication.

Conclusions:

This 8-year review showed DSAEK was the most commonly performed  transplant. Regrafting was the most common indication for corneal transplantation with overall graft survival of 75.5%.

Financial Disclosure:

None