Posters

The antibiofilm activity of probiotic lactic acid bacteria

Poster Details

First Author: S.Kivanc TURKEY

Co Author(s):    B. Akova   M. Kivanc   M. Kaya              

Abstract Details

Purpose:

Biofilm is defined as a matrix of extracellular polymeric material that is produced by bacteria and embedded in the microorganism that can cause the bacteria to adhere to any surface, interface or to each other, to exhibit different phenotypes depending on their growth rates and gene transcription. Biofilm formation stages include, adhesion, formation of mucous structure, mature biofilm, breakage and separation. Our aim was to investigate the effect of probiotic lactic acid bacteria on the biofilm formation of some pathogens isolated from the ocular surface.

Setting:

Eskisehir Technical University, Faculty of Science, Department of Biology

Methods:

The biofilm formation of pathogenic bacteria and the antibiofilm activity of  of probiotic bacteria was determined by microtitration plate method. The effect of filtrates and extracellular polysaccharides of 9 lactic acid bacteria on biofilm formed by 12 pathogenic bacteria was investigated.

Results:

The biofilm formation was noted with 12 pathogenic bacteria isolated from ocular surface. The probiotic lactic acid bacteria, L. pantarum, L. rhamnosus, L. brevis, L. acidophilus were shown to form antibiofilm.

Conclusions:

The filtrate ( supernatant) and  pellet ( extracellular polysaccharides)  parts of probiotic lactic acid bacteria prevent the biofilm formed by pathogenic bacteria at different rates. Further studies are needed for developing a anti-biofilm product.

Financial Disclosure:

None