Posters

Classification, risk factors, and outcomes for patients with blepharokeratoconjunctivitis (BKC) treated with Great Ormond Street Hospital treatment protocol

Poster Details

First Author: S.Hamada UK

Co Author(s):    J. Evans   M. Elalfy   K. Elsawah              

Abstract Details

Purpose:

Measure success of current treatment protocol at Great Ormond street Hospital and identify risk factors contributing to poor disease control.

Setting:

Great Ormond street Hospital,London, United Kingdom

Methods:

Retrospective review of 42 patients over 10 years treated by GOSH protocol designed for different stages of mild, moderate and severe BKC. The review included all children with BKC and excluded children with significant systemic disorders, atopy, vernal keratoconjunctivitis, or perennial allergic conjunctivitis. Data collected was Gender, age at onset of symptoms, referral source, age at presentation, follow up (years), activity/damage score of the worst affected eye at presentation and at last follow up and number of recurrences during study period.

Results:

Complete success was achieved in 21 patients (50%), partial success was achieved in 16 patients (38%), failure was noted in 5 patients (12%) although it should be noted that none of the patients had an activity score which was worse post-treatment compared to pre-treatment. Risk factors for poor control found to be acne rosacea. Age of onset, length of symptoms prior to referral, ethnicity and gender were found not to be risk factors for poor control. White Caucasians with BKC are at risk of a severe phenotype that is resistant to treatment.

Conclusions:

GOSH deals with some of the most complex cases of BKC in children. Cure of the disease is not always possible but following a strict regime of treatment (our protocol) will ensure maximum good outcomes.

Financial Disclosure:

None