Posters

Autologous serum for the treatment of grade 2 and 3 neurotrophic keratitis: one-year follow-up

Poster Details

First Author: S.Bagaglia ITALY

Co Author(s):    S. Zuccarini   A. Crisà   M. Ferrise   C. Mazzotta           

Abstract Details

Purpose:

To evaluate management of Iatrogenic Neurotrophic keratitis with autologous serum treatment in 34 patients affected by NK

Setting:

University Of Siena, Department of Ophthalmology, Siena, Viale M.Bracci, Italy. Villa Donatello, Viale A. Ragonieri, Firenze

Methods:

we enrolled 34 patients (19 female, 16 males) with diagnosis of Neurotrophic keratitis,  (mean age:72,1 ± 11) treated with autologous serum for 1 year. Patients where included in 3 groups according to recent NK classifications (stage I, II and III). Confocal microscopy evaluation (IVCM), anterior segment (AS.OCT)  Minimum corneal thickness MCT , and Best corrected visual acuity where performed at  15 days, 1 month 3 months 6 months  and 12 months after treatment.

Results:

36 patients showed a full recovery of corneal Neurotrophic keratitis starting form 1 month  after the beginning of treatment, BCVA increased froma a baseline 0,397 avg to0,22 logMAR at 12th month , MCT  increased from 356 μm at baseline  to 465 μm  at the end of follow up

Conclusions:

: according to literature and to our study results, autologous serum is a valid medical approach for the treatment of Neurotrophic keratitis.

Financial Disclosure:

None