Posters

Iridocorneal endothelial syndrome: case report of Chandler’s syndrome variant

Poster Details

First Author: M.Alves BRAZIL

Co Author(s):    H. Rodrigues   N. Valenti   A. Martins   D. Chianello           

Abstract Details

Purpose:

Report a rare case of Chandler’s Syndrome, to help in proper and early diagnosis and management

Setting:

Hospital Federal Servidores do Estado do Rio de Janeiro (HFSE); Rio de Janeiro, Brazil

Methods:

Female patient, 77 years old, hypertensive and diabetic, presenting pseudofacia in the right eye and diabetic retinopathy in both eyes. Has reported low visual acuity for 10 years. Present visual acuity of 20/400 and counting fingers to 30 centimeters. The intraocular pressure is 10/13mmHg. At the biomicroscopy examination, the right eye shows no abnormalities, but in the left eye presents leukoma, corectopia, posterior synechia and 3+/4 edema

Results:

Chandler’s syndrome is a rare condition characterized by abnormalities in the corneal endothelium, of unknow cause, follow by iridocorneal angle obstruction and iris abnormalities, such as iris atrophy. It is one of the variants of iridocorneal endothelial syndrome (ICE syndrome). It affects middle-aged adults with female predilection, unrelated to family history and usually unilateral. It does not present a consistent association with systemic diseases. The phylogenetic origin is still conjectural. The purpose of treatment is to prevent the increase of intraocular pressure (IOP) and cornea damage

Conclusions:

We report a patient with clinical features compatible with Chandler’s Syndrome: endotelial abnormalities, difuse corneal edema and abnormalities and corectopia. The disease is chronic and progressive. Early features can be observed is specular microscopy, gonioscopy and ultrasound biomicroscopy. More studies are necessary to describe the incidence of this disease, as well to confirm the etiology

Financial Disclosure:

None