Posters

Progressive axial-length-shortening detected after cataract surgery in a patient with juvenile cataract and CRYBA4 gene mutation

Poster Details

First Author: H.Mölder ESTONIA

Co Author(s):    N. Latina                    

Abstract Details

Purpose:

To report a case of progressive axial length (AL) shortening detected after cataract operation in a 20-year-old female patient.

Setting:

Silmalaser, Tallinn, Estonia.

Methods:

We present a 20-year-old female patient with a progressive axial length (AL) shortening detected after cataract surgery. Patient came to the clinic with a complaint on a blurry vision in her left eye. A posterior subcapsular cataract was detected in both eyes at the initial referral. After uneventful cataract surgery and implantation of multifocal intraocular lens, a hyperopic shift was detected in the operated left eye. 28 months later, preoperative measurements for the right eye revealed an  AL  shortening in both eyes. Gene tests revealed CRYBA4 gene mutation.

Results:

Literature was reviewed, but no similar cases of a progressive AL shortening after a cataract surgery were found. After a three-year follow-up a progression of AL shortening in both eyes was detected. Thus, in 3 years an AL of the right eye has shortened by 0,5mm and AL of the left eye by 0,49mm respectively.

Conclusions:

The reason and duration of a progressive AL shortening remain unclear. Theoretically, it could be due to a CRYBA4 gene mutation. Based on one case it is impossible to establish a connection between a CRYBA4 gene, progressive AL shortening and juvenile subcapsular cataract. This case highlights the importance of a careful consideration of all possible reasons for a refractive shift after cataract surgery.

Financial Disclosure:

None