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Management of spherophakia-associated glaucoma with lensectomy, anterior vitrectomy, and iris-claw lens implantation

Poster Details

First Author: A.Meshksar IRAN

Co Author(s):    M. Masoumpour   M. Nowroozzadeh   M. Razeghinejad              

Abstract Details

Purpose:

To report the effect of lensectomy, anterior vitrectomy and iris-claw lens implantation in microspherophakia/spherophakia related glaucoma.

Setting:

Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Methods:

In this retrospective study, patients with spherophakia/microspherophakia and glaucoma who had undergone lensectomy, anterior vitrectomy, and iris-claw lens implantation were included. Patients with history of previous intraocular surgery, lens dislocation into the vitreous cavity, or the need for combined lensectomy/glaucoma surgery were excluded. The corrected distance visual acuity (CDVA), intraocular pressure (IOP) and the number of antiglaucoma medications were measured and recorded preoperatively and at the 1st, 3rd, 6th, and 12th months after the operation,  and annually thereafter. The Cup-to-disc ratio and RNFL thickness analysis with OCT were also assessed at the final visit.

Results:

A total of 12 eyes from 6 patients with the mean age of 19±6 years and the mean postoperative follow up of 66±12 months were included. The mean CDVA (logMAR) was improved from 0.92±0.57 before surgery to 0.17±0.15 at the last follow-up examination (P=0.001). The mean IOP decreased from 21.2±3.9 mmHg at baseline to 15.0±1.5 mmHg at the last visit (P= 0.006); and the number of anti-glaucoma medications decreased from 1.9±0.7 to 0.8±0.7 (P = 0.006).  The IOP tended to continually decrease up to 3 years after surgery, and slightly increase thereafter.

Conclusions:

Lensectomy is an appropriate procedure for spherophakia-associated glaucoma, in which the abnormal lens shape and position is supposed to be the primary pathologic factor. In most cases the IOP could be controlled post-lensectomy with medication and no need for any type of glaucoma surgery. Concomitant iris-claw lens implantation not only improved the vision, but also did not compromise the IOP lowering effect of the procedure.

Financial Disclosure:

None

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