Posters

Choroidal evaluation in patients under alpha-lytic therapy

Poster Details

First Author: A.Coppola ITALY

Co Author(s):    M. De Bernardo   G. Salerno   G. Cembalo   P. Cornetta   M. Gioia   N. Rosa     

Abstract Details

Purpose:

to check eventual choroidal changes in patients with major risk of  Intraoperative  Floppy Iris Syndrome (IFIS), assuming that the changes induced by alpha-lytic drugs could  not solely be  limited to the iris, but could involve all the uveal tract.

Setting:

University Eye Clinic, Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno

Methods:

21 eyes of 21 patients with age range from 60 to 88 years (77 ± 7 years) in alpha-lytic therapy scheduled for cataract surgery in the fellow eyes were included in the study. All patients underwent EDI-OCT with Heidelberg Spectralis OCT at the first pre-operative visit and approximately one month after suspension of alpha-lytic therapy. The data were tested with the signed Wilcoxon rank test.

Results:

The mean choroidal thickness at the subfoveal  level was 229 ± 82.6 µm in the first pre-operative visit and 217 ± 84.3 µm one month after suspension, while 1.5 mm nasally from the fovea it was respectively 205 ± 88.8 µm and 202 ± 84.8 µm and 1.5 mm temporally from the fovea was 221 ± 59.4 µm and 204 ± 58.2 µm respectively.

Conclusions:

Measurements showed a statistically significant reduction in choroidal thickness one month after therapy discontinuation (p = 0.05). The decrease in choroidal thickness could be an important sign in deciding the timing for cataract surgery in these patients

Financial Disclosure:

None