Posters

Comparison of Panacea intraocular lens (IOL) power calculator with six other methodologies

Poster Details

First Author: F.Mostofian CANADA

Co Author(s):    P. Vezina-Martel   M. Koaik   P. Morales   K. Baig           

Abstract Details

Purpose:

We assess the accuracy of intraocular lens (IOL) power predictions made by the Panacea IOL and Toric Calculator compared to six other calculation methods. The Panacea is a recent calculator that unlike previous methods, considers real measures from Scheimpflug imaging to determine the power of the posterior corneal curvature, using the back to front corneal radii ratio (B/F ratio). This would prove useful in post-refractive cataract surgery when the B/F ratio is reduced.

Setting:

University of Ottawa Eye Institute, Ottawa. Canada.

Methods:

This is a retrospective case series of 115 eyes of 81 patients undergoing cataract surgery with no prior ocular history. IOL power predictions were calculated for one spherical IOL and two aspheric IOLs using: Panacea, Hoffer Q, Holladay I and II, SRK/T, Hill RBF and Barrett Universal II. The IOL power prediction were statistically compared using paired t-test and Bland- Altman plots with apriori set clinical limits of agreement (LoA) > +/- 0.2 Diopters.

Results:

On average, Panacea provides IOL power predictions significantly (p< 0.05) higher than Hoffer Q(+0.47D), Holladay I (+0.35D), Holladay II (+0.17D), SRK/T(+0.34D); with no significant difference with Barrett (+0.10D, p=0.61) or Hill RBF (+0.15D, p=0.26). Based on the Bland-Altman plots, Panacea compared to all calculators resulted in 95% LoA wider (mean= +/-1.04 D) than the clinically acceptable limits.  Low B/F ratio (<82%, p< 0.05) correlated with higher IOL power predictions by Panacea. Low axial length (< 20 mm, p< 0.05) correlated with lower IOL power predictions. The type of lens did not impact the results.

Conclusions:

The IOL power prediction determined using Panacea was not significantly different from the Barrett Universal II and Hill RBF. However, the IOL power obtained by Panacea was not in clinical agreement with the other calculators. The power prediction was higher in eyes with lower B/F ratios. Further studies are recommended to assess post-operative prediction errors of this novel calculator.

Financial Disclosure:

None