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Cataract extraction in patients with primary congenital glaucoma

Poster Details

First Author: B.Benito SPAIN

Co Author(s):    L. Morales-Fernández   J. Martínez-de-la-Casa   J. García-Feijoo              

Abstract Details

Purpose:

To assess incidence and risk factors of cataract extraction (CE) in patients with primary congenital glaucoma (PCG), surgical outcome and complications.

Setting:

Retrospective cohort study.

Methods:

108 with PCG were included. Data collected: need for CE and at what age, intraocular pressure (IOP) at diagnosis of PCG, required antiglaucomatous surgeries, possible mutation in the CYP1B1 gene and final visual acuity (VA). Among those patients who required CE: VA, IOP and complications were evaluated preoperatively and postoperatively. The data was analysed with STATA.

Results:

198 eyes of 108 patients were included, median follow-up of 8 years (range: 5-53). 32 eyes (16.2%) of 24 patients (22%) required CE. CE median age was 12,94 years (Interquartile range (IQR): 2.42-22). The main identified risk factors for CE were: antiglaucomatous surgeries (Hazard Ratio (HR) 1.48, p <0.001) and tubes (HR 2.78, p <0.001). Lens was implanted in 30/32 eyes and main complications were: IOP decontrol (n = 13), capsular fibrosis (n = 7), corneal decompensation (n = 4), lens subluxation (n = 4) and endophthalmitis (n = 1). VA improvement was observed after CE in 66.67% of eyes.

Conclusions:

There is a high incidence of cataract surgery in patients with PCG but generally outside of paediatric age. A greater risk of CE was identified in those patients with a greater number of antiglaucomatous surgeries, especially after valvular implantation. Despite the high rate of complications related to CE in PCG, good visual improvement was observed after surgery.

Financial Disclosure:

None

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