Posters

IFIS in female patients: is that an oxymoron?

Poster Details

First Author: M.Tsatsos GREECE

Co Author(s):    D. Peironidis   A. Lioura   D. Kehagia   G. Balanikas   N. Ziakas        

Abstract Details

Purpose:

Intraoperative Floppy Iris Sydrome (IFIS) was first recognised and described in 2005 by Chang et al. It is characterised by poor pupil dilatation, billowing of iris stroma, iris prolapse through corneal incisions and progressive intraoperative pupillary constriction. The incidence of IFIS can vary, representing between 2-3% of the entire cataract population but it can be higher than 50% in patients taking Tamsulosin – a selective α1adrenergic blocker, compared to with other non-selective α-adrenergic blockers such as Alfuzosin, Doxazosin and Terazosin. Although number of other medications have been implicated in IFIS, its presence in female patients remains an area of controversy

Setting:

Aristotle University of Thessaloniki A Ophthalmology Department

Methods:

We retrospectively reviewed all our female patients that were reported to suffer from IFIS during phacoemulsification surgery and analysed the associated factors.

Results:

Female patients with IFIS represent 1.4% of our total patients undergoing phacoemulsification over a period of 3 years. Pre-op BCVA was 0.26 and it significantly improved post-operatively to 0.72 (p=0.026). 74% underwent Phacoemulsification under topical anaesthesia, with 26% undergoing Phaco under subtenon's. 17% were under antipsychotic medication, 26% had PXF, 8.5% were IDDiabetics and 17% were on Doxazocin. 47% had stage 1 IFIS, 17% stage 2 and 36% stage 3. Of the 26% that had subtenon's anaesthesia only 4% showed stage 3 IFIS. There was no significant correlation between the stage of IFIS and final BCVA.

Conclusions:

Female patients are often treated with a-adrenergic antagonists but at a different dose or frequency than male patients. A large proportion of our patients with IFIS were under antipsychotic medication, whereas an equally large amount of patients had pharmacological history. Subtenon's anaesthesia appears to be associated with less severe IFIS.

Financial Disclosure:

None