Treatment of myopia and astigmatism in eyes with suspicious topography with PRK followed by accelerated CXL: PRK-Plus

Session Details

Session Title: Presented Poster Session: Keratorefractive Surgery Results II

Venue: Poster Village: Pod 2

First Author: : G.Kymionis SWITZERLAND

Co Author(s): :    G. Kontadakis   N. Voulgari   M. Grentzelos                 

Abstract Details

Purpose:

To evaluate the visual, refractive and topographic outcomes after simultaneous photorefractive keratectomy (PRK) and accelerated corneal cross-linking (CXL) for the correction of myopia and astigmatism in eyes with suspicious topography.

Setting:

Vardinoyiannion Eye Institute of Crete, Faculty of Medicine, University of Crete, Heraklion, Greece

Methods:

In this prospective, interventional case series, patients with suspicious topographic findings underwent simultaneous PRK and prophylactic accelerated CXL for the correction of their refractive error. Epithelium was mechanically removed. MMC was used after PRK for 20 seconds in all cases. Accelerated CXL was performed for 5 minutes with irradiance of 18 mW/cm2. Visual, refractive and topographic outcomes were evaluated preoperatively and at 5 years postoperatively.

Results:

Five patients (10 eyes) were enrolled in the case series. All eyes had suspicious topography with asymmetric steepening and/or skewed axis. Mean age of the patients was 29 years (22 to 44). Average preoperative spherical equivalent refraction was -2.74 ± 1.02. At last follow-up, all eyes were within 1.00 diopter (D) of target refraction, while a trend towards overcorrection was observed. None of the eyes lost any line of corrected distance visual acuity (CDVA) whereas 2 eyes gained one line of CDVA. All eyes showed corneal stability during the follow-up period. Mean demarcation line depth was 144.9 μm.

Conclusions:

PRK followed by prophylactic accelerated CXL (PRK plus) seems to be a valid option for the correction of the refractive error in this series of patients with suspicious topography without compromising corneal stability up to 5 years postoperatively.

Financial Disclosure:

None