Corneal density analysis in estimation of patients' corneal status after different modifications of endothelial keratoplasty

Session Details

Session Title: Presented Poster Session: Spotlight on Cornea

Venue: Poster Village: Pod 2

First Author: : S.Trufanov RUSSIA

Co Author(s): :    E. Salovarova   I. Novikov                    

Abstract Details

Purpose:

To compare the results of corneal densitometry (CD) after different modifications of endothelial keratoplasty (DSAEK and DMEK)

Setting:

Research Institute of Eye Diseases, Moscow, Russian Federation.

Methods:

50 DMEK and 50 DSAEK cases without previous corneal surgery and vision-limiting ocular comorbidities were included. Corneal densitometry of the optically relevant (0-2mm) zone by use of device Pentacam Scheimpflug HR (OCULUS, Germany), best-corrected visual acuity (BCVA) and central corneal thickness (CCT) were evaluated preoperatively and at 1, 6, and 12 months postoperatively.

Results:

CD of the optical zone decreased from 27.1±7.8 grayscale units (GSU) preoperatively to 19.2±3.8 GSU at 12 months after DSAEK. Respectively, CD decreased from 27.17±4.9 GSU before to 16.1±1.7 GSU at 12 months after DMEK. Compared with DSAEK, DMEK cases showed lower central CD at 1, 6 and 12 months postoperatively. At 12 months after surgery, median BCVA was 0.9 for the DMEK group and 0.8 for the DSAEK group. Postoperative median BCVA was better in the DMEK group for every examination time point.

Conclusions:

DMEK showed lower CD and better BCVA compared with DSAEK in 1, 6 (P<0,05) and 12 postoperative months. The present results suggest an optimal restoration of the corneal clarity achieved with DMEK. Financial Disclosure: None

Financial Disclosure:

None