Optic nerve perfusion analysis with glaucoma angio-OCT

Session Details

Session Title: Presented Poster Session: Glaucoma II

Venue: Poster Village: Pod 3

First Author: : S.García-Delpech SPAIN

Co Author(s): :    A. Hervás   P. Udaondo   E. Sanz Marco                 

Abstract Details

Purpose:

Optical Coherence Tomography-Angiography (OCT-A) detect changes in the perfusion of the optic disc in patients with glaucoma disease.

Setting:

The study was done at AIKEN clinic, Valencia, Spain.

Methods:

We studied 35 eyes of 20 patients using high-speed OCT (AngioVue, Imex). The amplitude-angular deviation algorithm (SSADA) of the divided spectrum is used to calculate the angiography of the three-dimensional optical disk. A disk flow index was calculated from 4 recorded scans. Widefield OCT scanning on nightclubs can measure the thickness of the retinal nerve fiber (NFL) layer. The variability is evaluated by the coefficient of variation (CV).

Results:

In normal eyes, a dense red microvascular is visible in angio-OCT. This network was attenuated in subjects with glaucoma. The disc flow rate was reduced by 25% in the glaucoma group (P = 0.003). (15% mild, 10% moderate, 5% severe). The sensitivity and specificity were 100% using an optimized cut. The flow index was highly correlated with the standard deviation of the visual field pattern.

Conclusions:

With the Angio-OCT, repeated measurements of the optic disc perfusion can be useful in the evaluation of glaucoma and its progression. More clinical investigations are necessary to confirm these promising results.

Financial Disclosure:

None