Biomicroscopic and anterior segment OCT findings in filtration blebs of XEN45 implant in the remodelling phase

Session Details

Session Title: Presented Poster Session: Glaucoma I

Venue: Poster Village: Pod 3

First Author: : M.Castany SPAIN

Co Author(s): :    J. Rigo Quera   S. Banderas   O. Pujol   A. Dou              

Abstract Details

Purpose:

Long-term qualitative analysis of XEN45 filtration blebs.

Setting:

Hospital Universitari Vall d'Hebron

Methods:

Cross-sectional observational study analyzing the filtration bleb after at least 6 months from the implantation of XEN45 with mitomycin C. Anterior segment OCT (AS-OCT) and anterior segment photographs were performed.

Results:

29 eyes of 24 patients were analyzed, with an average follow-up time of 13 months. In the photographs, we assessed the morphology of the filtering bleb (flat in 18 eyes, diffuse in 10 eyes, encapsulated in 1 eye), the subconjunctival visibility of the XEN45 implant (visible in 22 eyes and not visible in 7), and vascularization (avascular in 7 eyes). In AS-OCT, we assessed the presence of bleb (detectable in 11 eyes and not detectable in 18 eyes), diffuse or layered thickening of Tenon (9 cases), cystic pattern (5 cases), and the presence of intraluminal hyperreflective material (13 cases).

Conclusions:

Two predominant bleb patterns are observed: one group presents flat blebs with visible implant in the biomicroscopy and absence of bleb signs, with or without intraluminal hyperreflective material in AS-OCT. The other group presents diffuse blebs in the biomicroscopy, with diffuse or cystic pattern in the AS-OCT; the cases of not visible XEN45 and avascular blebs are found in this group. Studies with greater sample size are necessary to relate the morphological and functional characteristics of the filtering bleb.

Financial Disclosure:

None