The effect of nasal steroid injection for nasal polyp on intraocular pressure
Session Details
Session Title: Presented Poster Session: Glaucoma I
Venue: Poster Village: Pod 3
First Author: : C.Lee SOUTH KOREA
Co Author(s): : T. Lee J. Nam
Abstract Details
Purpose:
Intranasal corticosteroid injection, especially triamcinolone acetonide(TA), is used to in the management of nasal polyp after endoscopic sinus surgery(ESS). We examined the effects of nasal TA injection for nasal polyp on intraocular pressure (IOP) in patients with ESS surgery.
Setting:
This is randomized, double-blind, placebo-controlled study from January to December of 2018, department of ophthalmology & of Otolaryngology-Head and Neck Surgery in Ulsan university Hospital, University of Ulsan College of Medicine, Ulsan, South Korea
Methods:
Patients were randomized to TA injection (Group I, 20mg/ml, 1 ml) and placebo normal saline injection (Group II, 1 ml), There were total of 5 study visits: baseline and weeks 2,4,8,12 after injection. Primary outcome measure was IOP difference between two group at 4 week and secondary outcome measure was comparing of proportion of 21 mmHg over between two groups at all each visit.
Results:
Forty-five consenting patients complete the study -23 in the group I and 22 in the group II . There were no stastically significantly difference between groups in baseline characteristics and IOP at 4 week was not significantly difference between two groups with both eye; For right eye, 13.93±3.27 versus 14.68±2.78 mmHg in group I and group II, respectively(P=0.45) and for left eye, 13.40±2.88 versus 13.95±2.55mmHg in group I and group II, respectively(P=0.53). At each study visit, there were no significant difference of proportion of 21mmHg over between 2 groups (P> 0.05)
Conclusions:
TA injection to intravitreal and subconjunctval area may induce IOP increasing. However TA injection to nasal poly for management of postoperative complications with ESS was relative safe and effective method.
Financial Disclosure:
None
