Comparative outcomes of ab interno canaloplasty vs trabeculectomy in uncontrolled open-angle glaucoma

Session Details

Session Title: Presented Poster Session: Glaucoma I

Venue: Poster Village: Pod 3

First Author: : J.Izquierdo PERU

Co Author(s): :    N. Agudelo   B. Rubio   L. Cañola   K. Ruiz              

Abstract Details

Purpose:

To compare the efficacy and safety of AB interno Canaloplasty (ABiC) with Trabeculectomy in patients with uncontrolled primary open angle glaucoma (POAG).

Setting:

Glaucoma is the leading cause of irreversible blindness, the prevalence and projection number of glaucoma cases is 111.8 million in 2040.Trabeculectomy is the gold standard procedure when medical treatment fails to control IOP, frequently accompanied by numerous complications. MIGS are emerging; ABiC, lowers IOP both safely and effectively.

Methods:

Patients with prior diagnosis of uncontrolled POAG or PEX despite maximal tolerated medical therapy who received the surgical intervention studied were included; the study groups were divided according to the intervention: 26 eyes underwent trabeculectomy (Group I) and 16 eyes phacotrabeculectomy (Group III), 13 eyes underwent ABiC (Group II) and 30 eyes phacoABiC (Group IV). Outcome measures included IOP, glaucoma medication, visual acuity, complications and postoperative visits and reinterventions.

Results:

This study included 85 eyes.  Baseline IOP±SD was 22.4±8.7 mmHg in Group I and 19.6±3.8 mmHg in Group II, at 12 months were 12.6±2.2 mmHg and 13.4±2.7 mmHg respectively. The mean preoperative IOP±SD was 18.9±6.2 mmHg in Group III and 22.0±8.3 mmHg in Group IV, which decreased to 14.10±4.9 mmHg and 12.10±2.1 mmHg respectively at 12 months follow up. Glaucoma medication decreased was clinically significant; when comparing the groups I and II, III and IV there were no difference at 12 months follow up. Complications were higher in trabeculectomy groups.

Conclusions:

Both procedures have similar efficacy in reducing IOP, canaloplasty and phacocanaloplasty showed more safety results, with less postoperative visits. The trabeculectomy stand-alone procedure showed decrease in visual acuity clinically significant.

Financial Disclosure:

None