Comparative study of the functional range of vision of two different multifocal IOL designs

Session Details

Session Title: Moderated Poster Session: Finding the Right Pseudophakic Presbyopia Treatment

Venue: Poster Village: Pod 2

First Author: : C.Balachandran AUSTRALIA

Co Author(s): :    R. Lapid   R. Suryakumar                    

Abstract Details

Purpose:

To compare the functional range of vision of two multifocal intraocular lenses.

Setting:

Prospective, Randomized, Controlled, Masked, Multicenter Study.

Methods:

Subjects were randomly assigned (1:1 ratio) for bilateral implant with PanOptix IOL (Model TFNT00) or AT Lisa Trifocal IOL (Model 839MP). Distance, intermediate and near visual acuities (VA) and Binocular Defocus curve (DC) were measured at the 6M visit. To quantify useful functional range of vision for physiologically relevant acuity demands, DC was overlaid with VA demand for a target size equivalent to 0.1 LogMAR and plotted as a function of defocus. Area under the curve (AUC) metric was used to estimate useful functional range of acuity reserve between 1m (1D) and 40 cm (2.5D) and compared.

Results:

180 subjects were evaluated. Monocular UCVA was superior for PanOptix vs. AT Lisa at intermediate and near (0.10 +/-0.13; 0.00 +/-0.10 for PanOptix and AT Lisa respectively). A greater proportion of subjects in the PanOptix group showed higher AUC on the DC compared to AT Lisa. AUC estimate showed a greater mean overall area for PanOptix (0.36 +/- 0.11) compared to AT Lisa IOL (0.29 +/- 0.11) for defocus levels between -1 and 2.5D (p<0.001). Comparison between acuity demand and DC performance showed that PanOptix has ~2-3 lines of functional acuity reserve at intermediate (1.5D) and near (2.5D).

Conclusions:

Both IOLs provided good distance vision. Near and Intermediate VA were superior for PanOptix IOL. AUC analysis for the DC showed significantly better performance and functional acuity reserve for PanOptix vs. AT Lisa. AUC metric is a useful tool to understand acuity reserve to changing visual demands as a function of optical defocus and distance.

Financial Disclosure:

... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented