Anterior chamber characteristics after Descement's stripping automated endothelial keratoplasty in patients with Fuchs' dystrophy

Session Details

Session Title: Presented Poster Session: Surgical Cornea

Venue: Poster Village: Pod 2

First Author: : R.Karadag TURKEY

Co Author(s): :    K. Hammersmith   P. Nagra   C. Rapuano                 

Abstract Details

Purpose:

To compare anterior segment parameters in patients with Fuchs endothelial dystrophy (FED) who underwent Descemet stripping automated endothelial keratoplasty (DSAEK) in one eye and no corneal surgery in the fellow eye.

Setting:

Cornea Service, Wills Eye Hospital, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, USA

Methods:

This prospective study was conducted on 28 eyes of 14 patients with FED who underwent DSAEK in one eye at least one year prior (DSAEK group) and no corneal surgery in the fellow eye (control group). The mean age was 76.9±7.0 years. Each eye was analyzed with the anterior segment optical coherence tomography, specular microscopy and Scheimpflug imaging systems. There were no statistically significant differences in the mean central corneal thickness (CCT), central anterior chamber depth, anterior chamber angle parameters, cylinder and keratometry values between two groups (all p>0.05).

Results:

The paracentral corneal thickness, corneal volume, endothelial cell density and hexagonal cell ratio measurements were statistically significantly higher in the DSAEK group than the control (all p˂0.05), and anterior chamber volume in the DSAEK group was statistically significantly less than the control (p=0.046). While posterior and total corneal densitometry values in the DSAEK group were statistically significantly lower than the control (p˂0.001, p=0.011 respectively), there were no statistically significant differences in the anterior or middle corneal densities (p=0.108, p=0.134 respectively).

Conclusions:

We found that total corneal densitometry value was decreased in DSAEK group. Although DSAEK surgery does not affect the anterior chamber angle parameters, it decreases the anterior chamber volume and increases the corneal volume and paracentral corneal thickness due to addition of the DSAEK graft.

Financial Disclosure:

None