Long-term follow-up of a child with a permanent scleral lens in his right eye after corneal perforation in the setting of toxic epidermal necrolysis (TEN)

Session Details

Session Title: Presented Poster Session: Medical Cornea

Venue: Poster Village: Pod 3

First Author: : N.Demirkaya THE NETHERLANDS

Co Author(s): :    H. van Vliet   R. Lapid-Gortzak   C. Nieuwendaal   I. van der Meulen              

Abstract Details

Purpose:

Toxic epidermal necrolysis (TEN) is a devastating life-threatening disease with acute and chronic ocular complications. We describe the management and follow-up of a five year old child with acute TEN (presumably induced by Paracetamol) presenting with binocular total epithelial defects, developing severe chronic ocular complications, including corneal melt and perforation of the right eye as well as fulminant symblephara.

Setting:

Academic Medical Center (AMC), University of Amsterdam

Methods:

Repeated (over thirty times) amnion membrane transplantation (Prokera), serum eye drops, topical cyclosporine, systemic Cellcept, lubricants, scleral lens fitting

Results:

Despite intensive therapy with the above-mentioned therapies, our patient developed a large corneal perforation in his right eye, which was sealed with histoacryl glue covered by a scleral lens that the patient wore permanently, day and night, for approximately two years. At present, both corneas are intact, albeit severely scarred.

Conclusions:

In this very severe case of toxic epidermal necrolysis, the right eye could be preserved due to permanent wearing of a scleral lens

Financial Disclosure:

None