Endophthalmitis following cataract surgery in the cefuroxime era: changes in the bacterial spectrum

Session Details

Session Title: Presented Poster Session: Infection & Imaging

Venue: Poster Village: Pod 2

First Author: : C.Garcia-Saenz SPAIN

Co Author(s): :    Y. Andres-Alba   G. Rodriguez-Caravaca   M. Leal-Gonzalez   F. Pessanha   C. Del Prado-Sanchez   A. Arias-Puente        

Abstract Details

Purpose:

To describe the primary microbiological data of endophthalmitis following cataract surgery, as well as the influence of intracameral cefuroxime.

Setting:

Hospital Universitario Fundación Alcorcón (Madrid). Spain.

Methods:

Retrospective observational analysis of the bacteriology and susceptibility to cefuroxime on endophthalmitis following cataract surgery recorded in a 20-year period (1999–2018).

Results:

Intracameral cefuroxime as prophylaxis against endophthalmitis following cataract surgery was introduced in 2005 at our hospital.There were 46 cases of endophthalmitis in 29361 procedures, which constitutes an incidence rate of 0.16%. In 39 cases the patients did not receive prophylaxis with cefuroxime (incidence 0.59%), whereas in 7 cases they did (incidence 0.03%). Cultures were positive in 31 patients (67%), with a Staphylococcus origin in more than 70%, followed by Streptococcus sp. During the treatment period with cefuroxime (which included 22722 surgeries) 4 cultures were isolated: 1 Enterococcus faecalis, 1 methicillin-resistant Staphylococcus aureus, 1 methicillin-resistant Staphylococcus epidermidis and 1 Pseudomonas aeruginosa.

Conclusions:

The use of intracameral cefuroxime was an important protective factor against postoperative endophthalmitis. In the last years there has been a shift in pathogens from cefuroxime-sensitive to cefuroxime-resistant microorganisms.

Financial Disclosure:

None