A comparative study of the functional range of vision of two different multifocal IOL designs

Session Details

Session Title: Multifocal IOLs II

Session Date/Time: Monday 16/09/2019 | 08:30-10:30

Paper Time: 08:42

Venue: Free Paper Forum: Podium 1

First Author: : R.Lapid-Gortzak THE NETHERLANDS

Co Author(s): :    C. Balachandra   J. Schwiegerling   R. Suryakumar                       

Abstract Details

Purpose:

To compare the functional range of vision of two multifocal intraocular lenses: PanOptix IOL (Model TFNT00) and AT Lisa Trifocal IOL (Model 839MP).

Setting:

Prospective, randomised, controlled, masked, multi-centre Study.

Methods:

Subjects bilaterally implanted with PanOptix or AT Lisa IOL (ratio 1:1). Distance, intermediate and near visual acuities (VA), and Binocular Defocus curve (DC) for +2.0D to -5.0D range of induced defocus were measured at 4-6 months; VA assessors masked for IOL assignment. To quantify useful functional range of vision for physiologically relevant acuity demands, DC was overlaid with VA demand for a target size equivalent to 0.1 LogMAR and plotted as a function of defocus. Area under the curve (AUC) metric was used to estimate useful functional range of acuity reserve between 1 m (1D) and 40 cm (2.5D) and compared.

Results:

215 subjects enrolled; 180 randomised and evaluated. Monocular uncorrected VA were superior for PanOptix vs AT Lisa at intermediate and near (0.10 +/-0.13; 0.00 +/-0.10 respectively). At the 4–6 months, a greater proportion of PanOptix subjects showed higher AUC on the DC compared to AT Lisa. AUC estimate showed a statistically significantly greater mean overall area for PanOptix (0.36 +/- 0.11) compared to AT Lisa IOL (0.29 +/- 0.11) for defocus levels between -1 and 2.5D (p<0.001). Comparison between acuity demand and DC performance showed that PanOptix has ~2–3 lines of functional acuity reserve at intermediate (1.5D) and near (2.5D).

Conclusions:

Both IOLs provided good distance vision. Near and intermediate VA were superior for PanOptix IOL. AUC analysis for the DC showed significantly better performance and functional acuity reserve for PanOptix vs. AT Lisa. AUC metric is a useful tool to understand acuity reserve to changing visual demands as a function of optical defocus and distance.

Financial Disclosure:

gains financially from product or procedure presented, research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, receives non monetary benefits from a competing company, receives consulting fees, retainer, or contract payments from a competing company, receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, is employed by a for profit company with an interest in the subject of the presentation