Corneal stromal roughness following LASIK flap-creation with four different femtosecond lasers: IntraLase, Visumax, LenSx and iFS – an atomic force microscopy study

Session Details

Session Title: LASIK & PRK I

Session Date/Time: Sunday 15/09/2019 | 16:30-18:00

Paper Time: 16:54

Venue: Free Paper Forum: Podium 3

First Author: : A.Katsanos GREECE

Co Author(s): :    J. Gros-Otero   S. Ketabi   R. Cañones-Zafra   S. Casado   A. Parafita-Fernández   M. Teus              

Abstract Details

Purpose:

To compare the corneal stromal roughness induced by femtosecond lasers when LASIK flaps are cut in porcine eyes.

Setting:

IMDEA Nanociencia Institute, Clínica Novovisión & Clínica Rementeria, Madrid, Spain. Principe De Asturias Hospital, University of Alcala, and Universidad Europea de Madrid, Spain.

Methods:

Twelve enucleated porcine eyes (3 for each Femtosecond laser: IntraLase, Visumax, LenSx and iFS) were used. Standard femtosecond laser parameters were used. After a LASIK flap was cut, the stromal bed roughness was assessed using a JPK NanoWizard II® atomic force microscope in contact mode immersed in liquid, using Olympus OMCL-RC800PSA commercial silicon nitride cantilever tips. Measurements were made in 10 regions (surface area: 20μm x 20μm) of the central stromal bed of each specimen, at 512x512 resolution. We evaluated the surface roughness using the root-mean-square (RMS) deviation from a perfectly flat surface within the analyzed area.

Results:

The RMS corneal stromal bed roughness was: 360±120 nm for the IntraLase, 230±100 nm for the Visumax, 370±100 nm for the LenSx, and 430±150 nm for the iFS. The smoothest stromal bed surface after a femtosecond laser cut was obtained with the Visumax Laser. Compared to the other groups, this difference was statistically significant (p<0.05).

Conclusions:

The stromal bed roughness after a femtosecond laser cut varies depending on the device studied. Visumax is the laser that obtains the smoothest surface among the ones analyzed.

Financial Disclosure:

None