Window absorption corneal cross-linking in the treatment of severe corneal ulcers: long-term follow-up

Session Details

Session Title: Ocular Infections & Other Topics

Session Date/Time: Sunday 15/09/2019 | 08:00-10:00

Paper Time: 08:06

Venue: Free Paper Forum: Podium 4

First Author: : P.Rosetta ITALY

Co Author(s): :    F. Camesasca   E. Legrottaglie   A. Borgia   P. Vinciguerra                    

Abstract Details

Purpose:

We treated severe infectious corneal ulcers with antibiotic therapy and Window Absorption corneal cross-linking (CXL-WA).

Setting:

Humanitas University Clinical and Research Center, Rozzano, Milan, Italy

Methods:

Ten eyes with severe keratitis and corneal melting (4 Pseudomonas Aeruginosa, 2 Staph. Epidermidis, 1 coagulase-negative Staph., 1 Strept. pneumoniae, 2 Acanthamoebae) were treated with antibiogram-guided topical antibiotic therapy and CXL-WA. Minimum follow-up was one year.

Results:

Treatment healed corneal infection. OCT showed long-term increase in stromal density, tomographic stability, and no ectasia even in thinned corneas (<300μm). Demarcation line was deeper than 200 microns.

Conclusions:

CXL-WA-mediated increase in corneal strength stabilized these severely damaged preventing more invasive approaches.

Financial Disclosure:

None