Evaluation of corneal morphology in patient with hemifacial spasm

Session Details

Session Title: Ocular Pathology/Education & Training

Session Date/Time: Tuesday 17/09/2019 | 14:00-16:00

Paper Time: 14:12

Venue: Free Paper Forum: Podium 4

First Author: : D.Ulusoy TURKEY

Co Author(s): :    E. Ulusoy   Z. Duru   A. Çiçek                       

Abstract Details

Purpose:

To determine if the corneal topographic parameter values, individual corneal layer thicknesses, and its endothelial layer morphology are different in patients with hemifacial spasm (HFS) than in the control contralateral eye.

Setting:

Prospective study

Methods:

This study was designed as a prospective study. Among patients who applied to our hospital within the last 3-year period, those with HFS in one eye (study eyes) and a completely normal contralateral eye (control eyes) were included in this tudy. In addition to a complete ophthalmologic examination, all patients were scanned by Pentacam Scheimpflug camera, and a corneal endothelium cell count was taken using a Topcon Specular Microscope. Also, the thickness of the corneal sublayers were measured on the central cornea with anterior segment module of spectral domain optical coherence tomography (AS-OCT).

Results:

Twenty-eight patients (16 females and 12 males) were evaluated. Steep K, K-max and astigmatism values were significantly higher in study eyes of HFS patients than in control eyes (p<0.05, for all). In addition the total corneal thickness and corneal stromal thickness measurements in study eyes were statistically significant thinner than control eyes (p=0.04 and p<0.001, respectively). Specular microscopy parameters were not statistically significant between study eyes and control eyes (p>0.05 for all).

Conclusions:

Corneal stromal thinning suggests that chronic exposure to hypoxia may induce this effect through extracellular matrix remodeling and losses in collagen framework content in HFS patients.

Financial Disclosure:

None