Validation of corneal topographic and aberrometric measurements obtained by colour light-emitting diode reflection topography in healthy eyes

Session Details

Session Title: Advanced Tools for Outcome Assessment

Session Date/Time: Tuesday 17/09/2019 | 08:30-10:30

Paper Time: 08:36

Venue: Free Paper Forum: Podium 4

First Author: : D.Piñero Llorens SPAIN

Co Author(s): :    A. Molina-Martin   V. Camps   M. Caballero   D. de Fez   H. Fukumitsu                 

Abstract Details

Purpose:

To evaluate the intrasession repeatability of anterior corneal topographic and aberrometric measurements provided by a color-LED topographer as well as their interchangeability with those provided by a Scheimpflug-based system in healthy eyes.

Setting:

Department of Optics, Pharmacology and Anatomy of University of Alicante, Alicante, Spain

Methods:

Thirty-five healthy eyes of 35 patients (age, 16-66 years) were enrolled. A complete eye examination was performed in all cases including a complete corneal analysis with the Scheimpflug-based system Pentacam (Oculus Optikgeräte) (one measurement) and the Cassini system (i-Optics) (three consecutive measurements). Intrasession repeatability of Cassini measurements was assessed with the within-subject standard deviation (Sw) and the intraclass correlation coefficient (ICC). The Bland-Altman analysis was used to evaluate the agreement between both devices.

Results:

Mean Sw for keratometric readings was 0.02 mm (ICC≥0.992), ranging between 0.16 and 0.05 D (ICC: 0.930-0.978) for anterior and total astigmatic measurements. Mean Sw for asphericity and corneal diameter were 0.06 (ICC: 0.926) and 0.03 mm (IC: 0.997), respectively. Aberrometric parameters showed ICCs≥0.816, except for Z42 (ICC: 0.741) and Z44 (ICC: 0.544). When comparing devices, significant differences were found for most of topographic and aberrometric data (p≤0.044). Likewise, ranges of agreement between devices were clinically relevant (keratometry>0.06 mm; total astigmatism>0.69 D; asphericity: 0.35; 2nd/3th/4th order Zernike terms: > 0.20/0.13/0.01 μm).

Conclusions:

Consistent anterior corneal topographic, total corneal astigmatic and aberrometric measurements are obtained with color-LED topography in healthy eyes, which are not interchangeable with those provided by Scheimpflug-based topography.

Financial Disclosure:

travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented