Experimental comparison between femtosecond laser-assisted and manual capsulotomy for eyes with zonular dehiscence

Session Details

Session Title: Femtolaser-Assisted Cataract Surgery (FLACS)

Session Date/Time: Monday 16/09/2019 | 08:30-10:30

Paper Time: 09:32

Venue: Free Paper Forum: Podium 4

First Author: : S.Yaguchi JAPAN

Co Author(s): :    H. Bissen-Miyajima   K. Minami                          

Abstract Details

Purpose:

The use of femtosecond laser is advantageous in creating a complete circular capsulotomy even for eyes with zonular dehiscence. This experimental comparison was aimed to evaluate the efficacy of femtosecond laser assisted capsulotomy with manual continuous curvilinear capsulorhexis (CCC) using porcine eye model of zonular dehiscence.

Setting:

Department of Ophthalmology, Tokyo Dental College Suidobashi Hospital.

Methods:

Forty enucleated porcine eyes were used in this study. To observe the zonule and capsule, a whole iris was removed in all eyes. Eye model of zonular dehiscence was made by dissecting 180 degrees of zonules using diathermy. Anterior capsulotomy was created either with femtosecond laser LenSX® (Alcon) under the setting of 5.70-mm diameter (laser group) or with manual procedure using a 5.75-mm CCC marker and capsule forceps (manual group). The mean diameter of longest and shortest diameters of each capsulotomy, as well as the ellipticity were compared in the eye with zonular dehiscence and without zonular dehiscence (control).

Results:

The mean diameter and ellipticity of the capsulotomy of laser group were 7.6±0.3 mm and 1.6±0.9% in the eyes with zonular dehiscence, and 7.4±0.3 mm and 1.7±1.4% in control eyes. No statistical difference was found between the eye with zonular dehiscence and the control. The mean diameter and ellipticity of manual group were 7.3±0.6 mm and 9.0±6.0% with eyes with zonular dehiscence. Compared with those of control eyes (6.1±0.5 mm and 2.5±1.9 %), the capsulotomy was significantly larger and ovalized (P=0.0003, 0.008). The circularity of laser group in eye with zonular dehiscence was better compared to manual group (P=0.004).

Conclusions:

The experimental comparison of porcine eyes confirmed the effectiveness of femtosecond laser assisted capsulotomy in cases with 180-degree zonular dehiscence. The further evaluation in human eye model is necessary.

Financial Disclosure:

gains financially from product or procedure presented