An experimental bench investigation of a new monofocal IOL for its design trade-off: refractive power shift and consequent image quality impact

Session Details

Session Title: Extended-Depth-Of-Focus IOLs I

Session Date/Time: Sunday 15/09/2019 | 14:00-16:00

Paper Time: 15:30

Venue: Free Paper Forum: Podium 1

First Author: : S.Lane USA

Co Author(s): :    Z. Xu   J. Lutkenhaus   H. Zhang   S. Lee   X. Hong                 

Abstract Details

Purpose:

A new monofocal IOL (Model ICB00, J&J Vision) has a modified aspheric anterior surface and is indicated to improve vision for intermediate tasks. This bench study experimentally examines the design features of this new IOL and the optical consequences of design trade-off.

Setting:

Laboratory bench study at Alcon Research LLC, Fort Worth, Texas, USA.

Methods:

Refractive power and image quality (MTF) were measured using model eyes per the guidelines established in ISO 11979-2. Additionally, the shift in power and image quality were assessed as a function of pupil size. Lens surface was profiled and fitted with higher order aspheric terms in order to simulate the lens performance (refractive power shift and image quality changes). In all the tests, commercially available aspheric monofocal lenses (AcrySof SN60WF and Tecnis ZCB00) were used as controls.

Results:

ICB00, unlike other aspheric monofocal IOLs, had more than 0.25D refractive power shift (up to 0.7D for the IOL alone) when IOL aperture was changed from 3mm to 2mm. ICB00 image quality, when based on 3mm aperture best focus, was reduced by up to ~30% and ~70% vs. aspheric monofocal IOLs at 3 mm and 2mm IOL apertures respectively. Profilometry fitting results showed that the anterior surface of ICB00 has up to twelfth order of aspheric terms. The optical simulation results closely matched the bench data, confirming progressively larger power shift and decrease in image quality at smaller pupil diameters.

Conclusions:

ICB00 IOL has a high-order aspheric anterior surface design, which results in a progressive refractive power shift at smaller pupil diameters but with a coincident reduction in optical quality in comparison to other commercially available aspheric, monofocal IOLs. Bench and theoretical simulation confirmed that these optical quality trade-offs are expected from using higher-order aspheric surface. Clinical studies are warranted to further interpret and translate these results on refractive and visual quality outcomes.

Financial Disclosure:

is employed by a competing company