Posters

Evaluation of conjunctival vascularity in healthy individuals and glaucoma patients using optical coherence tomography angiography

Poster Details

First Author: J.Seo KOREA

Co Author(s):                     

Abstract Details

Purpose:

To investigate whether conjunctival vascularity could be evaluated using optical coherence tomography angiography (OCT-A), and to compare conjunctival vascularity parameters between healthy individuals and glaucoma patients.

Setting:

Pusan National University Yangsan Hospital, Yangsan, Korea

Methods:

Superior conjunctival scans were obtained using OCT-A external mode. For evaluation of conjunctival vascularity, a blinded observer carefully outlined whole conjunctiva and limbal conjunctiva on the original OCT-A image, using a semi-automated program, which calculated the density of color, brightness, and threshold of the selected area. A linear mixed model analysis of conjunctival vascularity in healthy individuals was performed. For comparison of conjunctiva vascularity in glaucoma patients according to conjunctival type, the paired t-test was performed. To compare conjunctival vascularity between healthy individuals and glaucoma patients, a linear mixed model analysis was performed with false discovery rate correction.

Results:

Sixty-two eyes of 31 healthy individuals and 68 eyes of 68 glaucoma patients were enrolled. Vascularity parameters measured by OCT-A demonstrated excellent inter- and intra-observer reproducibility. The color density of the whole conjunctival area was higher than that of the limbal conjunctival area in both healthy individuals and glaucoma patients. The limbal conjunctival vascularity in glaucoma patients was significantly higher than that in healthy individuals, whereas the whole conjunctival vascularity in glaucoma patients was higher than that in healthy individuals with marginal significance.

Conclusions:

Conjunctival vascularity can be evaluated using OCT-A. In glaucoma patients, limbal conjunctival vascularity parameters were higher than those in healthy individual.

Financial Disclosure:

None