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Orbital cellulitis: why does it not subside?

Poster Details


First Author: E.Karasavvidou GREECE

Co Author(s): A. Michonidou   K. Boboridis   D. Balatsoukas   E. Kanonidou           

Abstract Details

Purpose:

Metastatic tumors account for 1-13% of all orbital tumors. In 15% of these cases, orbital metastasis are the initial presentation of the disease. Our purpose is to report a case of metastatic prostate adenocarcinoma that was initially misdiagnosed as orbital cellulitis.

Setting:

Department of Ophthalmology, Hippokrateion General Hospital of Thessaloniki, Thessaloniki, Greece

Methods:

An 80-year-old male presented with a 10-days history of right eyelid oedema, conjunctival chemosis and proptosis accompanied by restricted ocular motility. He denied any pain or double vision. His past medical history included hypertension, coronary artery disease, aortic stenosis, dyslipidemia, benign prostatic hyperplasia and thyroid disease. Clinical examination showed best corrected visual acuity 20/25 in both eyes with no afferent pupillary defect. Intraocular pressure was normal and dilated fundoscopy revealed no pathology.

Results:

Computed Tomography of the orbits was performed, which demonstrated right orbital cellulitis and the patient was admitted to Ophthalmology department in order to start on broad-spectrum antibiotics. Blood tests were within normal limits. Due to lack of response to antibiotic therapy and after excluding the presence of sinusitis and thyroid ophthalmopathy, we decided to proceed with orbital biopsy. Histopathological results showed metastatic adenocarcinoma from a prostatic origin.

Conclusions:

Orbital metastasis can present as orbital inflammation in 5% of the cases mimicking atypical orbital cellulitis. Thus, it should always be taken into consideration in differential diagnosis along with thyroid ophthalmopathy.

Financial Disclosure:

None

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