Posters

The relation between retinal vessel diameter with both macular thickness and other variables using OCT in middle-aged Caucasians

Poster Details

First Author: M.Geneid FINLAND

Co Author(s): M. Geneid   J. Uusitalo   V. Saarela   J. Liinamaa           

Abstract Details

Purpose:

To study the relationship between retinal vessel diameter (RVD) with macular thickness, macular volume, retinal nerve fiber layer (RNFL) and optic nerve head (ONH) parameters in a normal population cohort of middle-aged Caucasians.

Setting:

The Northern Finland Birth Cohort (NFBC) Eye study. Dept. of Ophthalmology, Oulu University Hospital, MRC Oulu and PEDEGO Research Unit, University of Oulu, Oulu, Finland

Methods:

We collected data from 3070 individuals (6140 eyes). Using a semi-automated computer-assisted program we measured Central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE). Macular and ONH parameters were assessed using Optical Coherence Tomography (OCT). Data from 2328 persons were analyzed.

Results:

Larger RVD was associated with thicker macula and increased macular volume, each standard deviation (SD) increase in macular thickness and volume was associated with a 3.37 μm and a 3.28 μm increase in arteriolar diameter and a 5.16 μm and a 5.15 μm increase in venular diameter respectively (all P<0.001). Larger rim area and RNFL thickness were associated with larger RVD, each SD increase in rim area and RNFL thickness was associated with a 0.98 μm and a 3.05 μm increase in arteriolar diameter and 1.86 μm and a 4.91 μm increase in venular diameter respectively (all P<0.001).

Conclusions:

Increased macular thickness, macular volume, RNFL thickness, and optic nerve rim area were found to be associated with larger RVD in all subjects. This study clarifies the anatomical correlations between both macular and ONH parameters with RVD for middle-aged Caucasians, that can be used in further studies investigating the vascular etiology in eye diseases.

Financial Disclosure:

None