Posters

Evaluation of macular function and thickness after corneal cross-linking for progressive keratoconus

Poster Details

First Author: M.Dettoraki GREECE

Co Author(s): K. Droutsas   A. Lazaridis   G. Kymionis   M. Moschos           

Abstract Details

Purpose:

To assess any changes in macular function and foveal morphology in patients with progressive keratoconus undergoing accelerated corneal cross-linking (CXL).

Setting:

University Ophthalmologic Clinic in Tertiary Referral Hospital

Methods:

A prospective study of 9 eyes of 8 patients with progressive keratoconus undergoing accelerated CXL was performed. All patients underwent an ophthalmic examination including visual acuity assessment, slit lamp biomicroscopy, dilated fundoscopy, corneal topography, spectral domain optical coherence tomography scan and multifocal electroretinography (mfERG) at baseline, 2 weeks and 6 weeks after operation.

Results:

Best corrected visual acuity was 0,21±0,24 preoperatively and did not differ significantly at 2 weeks (0,19±0,17, p=0,82) and 6 weeks (0,16±0,18, p=0,65) postoperatively. Central foveal thickness did not change at 2 weeks and 6 weeks after operation compared to baseline (p=0,53 and p=0,93, respectively). Retinal response density of mfERG significantly decreased at 2 weeks postoperatively compared to baseline (p=0,008) but did not differ from the baseline value 6 weeks postoperatively in the fovea (p=0,95). Similarly, P1 latency significantly decreased at 2 weeks (p=0,04) postoperatively but did not change at 6 weeks (p=1,00) postoperatively compared with baseline in the fovea.

Conclusions:

Accelerated CXL seems to be a safe procedure with no short term functional or morphological effects on the macula of keratoconus patients.

Financial Disclosure:

None