Posters

Boston type 1 keratoprosthesis outcomes in the non-elderly population

Poster Details

First Author: T.Trinh CANADA

Co Author(s): N. Sorkin   Z. Mednick   G. Santaella   D. Rootman   C. Chan   A. Slomovic     

Abstract Details

Purpose:

To determine the outcomes of Boston type I keratoprosthesis implanted in non-elderly patients.

Setting:

Single tertiary referral corneal department in Toronto, Canada.

Methods:

A retrospective case series was performed on patients aged 18 to 70 years of age who received the Boston type I keratoprosthesis between January 1st 2008 and 31st October 2018. Initial diagnosis, immediate-pre-operative diagnosis, interval visual acuity, keratoprosthesis retention and post-operative complications were recorded for each patient.

Results:

Twenty-six Boston type I Keratoprostheses were implanted into 26 eyes of 24 patients. The mean age of patient was 58 years. The most common indications were failed penetrating keratoplasty (n=15, 60%) limbal stem cell disease (n=12, 48%) and pseudophakic/aphakic bullous keratopathy (n=2, 8%). All patients had pre-operative visual acuity of <20/100 and 7 of 25 patients (30%) maintained visual acuity of 20/200 or better at 1 year. Median follow up length was 48 months (range: 3-92). Device retention at 4 years was 86.9%. Most common complication was retroprosthetic membrane formation (n=19, 86.2%).

Conclusions:

This is the first study reporting on Boston type I keratoprosthesis in the non-elderly patient setting. Boston Keratoprosthesis is an effective treatment modality for managing corneal blindness in these patients. Visual outcomes at one year were reduced compared to the initial Multicentre Boston Type I Keratoprosthesis study. Aniridic patients tend to require earlier intervention with the Boston Keratoprosthesis. Poorer visual outcomes were associated with posterior segment pathology unrelated to corneal disease.

Financial Disclosure:

None