Novel concept of post-operative intraocular lens position prediction using pre-operative and intra-operative measurements

Session Details

Session Title: Cataract
Session Date/Time: Saturday 16/02/2019 | 08:30-11:00
Paper Time: 08:48
Venue: Hall Trianti

First Author: N.Hirnschall AUSTRIA
Co Author(s): S. Amir-Asgari  J. Hienert  H. Matz  M. Trost  O. Findl     

Abstract Details

Purpose:

To use pre-operative and intra-operative optical coherence tomography based measurements to predict the intraocular lens position after cataract surgery.

Setting:

VIROS, Vienna Institute for Research in Ocular Surgery, Hanusch Hospital, Vienna, Austria

Methods:

This prospective study included patients scheduled for cataract surgery. All patients received either a plate haptic IOL (Asphina, Carl Zeiss Meditec AG, Germany), or an open loop haptic IOL (ZCB00, Johnson&Johnson, USA). Pre-operatively, optical biometry was performed (IOLMaster 700, CZM). Intra-operatively, a prototype set-up was used that allowed to perform time domain OCT scans of the anterior eye segment (Visante connected with OPMI Lumera 200, both CZM). iACD was measured and used to predict the post-operative IOL position. Optical biometry and subjective refraction and autorefraction (Topcon RM 8800, Topcon, Japan) were performed 2 months after surgery.

Results:

In total, 203 eyes of 203 patients were included. A partial least square regression model for ACD 2 months after surgery was generated and the predictive power of the iACD (0.48) was highest, followed by axial eye length (0.45), followed by pre-operatively measured ACD (0.30). These findings were confirmed in a boot strapping model. Regression models combining pre-operative and iACD resulted in a further significant improvement.

Conclusions:

iACD measurements were shown to be superior to pre-operative ACD measurements for open loop IOLs and plate haptic IOLs. Combining pre- and iACD measurements improved the prediction further.

Financial Disclosure:

... is employed by a for-profit company with an interest in the subject of the presentation