Treatment of myopia and astigmatism in eyes with suspicious topography with PRK followed by accelerated CXL: PRK-Xtra

Session Details

Session Title: Refractive
Session Date/Time: Friday 15/02/2019 | 08:30-10:00
Paper Time: 08:42
Venue: Room MC3

First Author: G.Kontadakis USA
Co Author(s): N. Voulgari  M. Grentzelos  G. Kymionis           

Abstract Details

Purpose:

Refractive surgery in corneas with suspicious topography is a great challenge in order to avoid the risk of ectasia development. Combination of photorefractive keratectomy (PRK) with standard protocol corneal collagen crosslinking (CXL) has been introduced in the past for the treatment of keratoconus, but the predictability of the refractive results was suboptimal. The purpose of this study is to present the results of PRK combined with accelerated CXL for the correction of myopia and astigmatism in patients with suspicious topographic findings

Setting:

University of Crete, Institute of Vision and Optics

Methods:

Five patients (10 eyes) were included in the study. All eyes had suspicious topography with asymmetric steepening and/or skewed axis. Average age of the patients was 29 years (22 to 44). Average spherical equivalent refraction was -2,74 (standard deviation [SD] 1.02). All patients underwent mechanical debridement of epithelium in an 8mm diameter and photorefractive keratectomy with mitomycin C application for 20sec, followed by accelerated CXL. Crosslinking was performed for 5 minutes with irradiance of 18mW/cm2.

Results:

All patients were followed for 4 years postoperatively. At last follow up nine out of ten eyes were within 0.50 diopter of target refraction and all were within 1 diopter. None of the eyes lost a line of best corrected visual acuity, whereas 2 eyes gained one line. All corneas remained stable during follow up. Average central depth of demarcation line was 144.9μm.

Conclusions:

In this group of eyes with suspicious topography, PRK followed by accelerated CXL (PRK-Xtra) was a valid option for the correction of their refractive error, without compromising stability of topography up to 4 years postoperatively.

Financial Disclosure:

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