Effects of intraocular lens glistenings on visual function: A prospective study and presentation of a new glistenings grading methodology

Session Details

Session Title: Cataract
Session Date/Time: Saturday 16/02/2019 | 08:30-11:00
Paper Time: 09:24
Venue: Hall Trianti

First Author: N.Stanojcic UK
Co Author(s): D. O'Brart  N. Maycock  C. Hull           

Abstract Details

Purpose:

To investigate the effect of intraocular lens (IOL) glistenings on visual performance and evaluate a new glistenings grading methodology.

Setting:

King’s College London Frost Eye Research Unit, Department of Ophthalmology, St Thomas’ Hospital, London, England, UK.

Methods:

Thirty-four patients (34 eyes) were recruited. Corrected distance visual acuity (CDVA), mesopic gap acuity (MGA), functional contrast sensitivity (FCS) and forward light scatter (FLS) were measured (Advanced Vision and Optometric Tests, City Occupational Ltd, London, UK). The IOL centre was imaged and glistenings density graded by three observers using the Miyata scale and a new system. Inter-rater reliability, association between the two grading scales and correlations between glistenings grades and visual performance parameters were evaluated.

Results:

The intra-class correlation coefficient between graders for the new grading system was 0.769, 95% CI [0.636, 0.868]. There was a significant association between the Miyata scale and the new grading system for all graders (rs= 0.533 to 0.895; P≤0.001). There was no association between CDVA or MGA and glistenings grade (rs= -0.098, P=0.583 and rs=0.171, P=0.359 respectively). There was no association between FCS at mesopic light levels and glistenings grade (rs= -0.032, P=0.864) or the straylight parameter and glistenings grade (rs= 0.021, P=0.916). No association was found between the integrated straylight parameter and glistenings grade (rs= 0.078; P=0.701).

Conclusions:

The new glistenings grading scale was highly reproducible. Glistenings in the same hydrophobic acrylic IOL after cataract surgery were not associated with changes in visual function.

Financial Disclosure:

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