Extreme ocular hypotension treated with platelet rich plasma (E-PRP)

Session Details

Session Title: Cornea & Miscellaneous
Session Date/Time: Friday 15/02/2019 | 10:30-12:30
Paper Time: 12:06
Venue: Room MC3

First Author: O.Abd AlRahman EGYPT
Co Author(s): A. E. Rodriguez  J. Alio del Barrio  J. L. Alio           

Abstract Details

Purpose:

To report a new surgical technique for treatment of ocular hypotony in 3 eyes by injecting autologous platelet-rich plasma in the anterior chamber.

Setting:

This new surgical technique was carried at Vissum Instituto Oftalmologico de Alicante, University Miguel Hernandez, Alicante, Spain .

Methods:

Platelet rich plasma (E-PRP) is used to enhance wound healing and stimulates tissue regeneration; this effect is attributed to essential growth factor and cell adhesion molecules.The first was Axenfield Rieger’s syndrome with severe chronic hypotony reaching zero mmHg following glaucoma surgey,the second was a perforation in a dystrophic cornea with a diffuse deep ulcer leaking in which the technique avoided a corneal graft from being performed and the third was in a cyclodialysis induced by a microstent bypass which led to chronic hypotonia and macula edema.All cases were injected by 0.3 ml of E-PRP once in the anterior chamber.

Results:

Intraocular pressure (IOP) was measured by Goldman’s applanation tonometry 1st hr after intracameral injection of E-PRP, it was 30 mmHg then 6 hrs later it became 18mm Hg. During the follow-up periods of at least 6 months, IOP was controlled and remained stable. YAG laser was done to dissolve the remnants of clotted E-PRP in the anterior chamber. No filtration or hypotony were observed. The distant unaided visual acuity was improved in all cases.

Conclusions:

Injecting platelet rich plasma has no intra or postoperative complications. Intracameral platelet rich plasma (E-PRP) injection showed to be effective, rapid, and safe procedure in treating severe chronic hypotony.

Financial Disclosure:

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