10 year outcomes of CXL combined with partial topo-guided excimer (TGL) (Athens Protocol (AP) for keratoconus (KC)

Session Details

Session Title: Refractive
Session Date/Time: Friday 15/02/2019 | 08:30-10:00
Paper Time: 08:54
Venue: Room MC3

First Author: A.Kanellopoulos GREECE
Co Author(s): F. Xhani                 

Abstract Details

Purpose:

To report the safety and long-term efficacy of the Athens Protocol, focusing on refractive, topographic and pachymetric changes of treated keratoconic patients over a 10-year follow up.

Setting:

LaserVision gr Clinical and Research Eye Institute, Athens, Greece

Methods:

This is an observational case series of one hundred forty-four eyes treated for progressive keratoconus with the Athens Protocol procedure. Preoperative and postoperative examinations on average 10 years after treatment included visual acuity, refraction, corneal topography (keratometry values), tomography and corneal thickness.

Results:

UDVA showed improvement at 1y-follow-up(0.19±0.17 to 0.53±0.21)and improved further more slightly up to 10y(0.55±0.19).CDVA increased from 0.59±0.21 to 0.80±0.17(1y-postop) and to 0.81±0.19(10y-postop).Minimal corneal thickness decreased from 468.74±35.05um to 391.14±40.07um(P<.01; 1y-postop) and then increased to 395.42±32.21μm(10y-postop).K1 decreased from 44.82±2.95D to 41.33±3.77D(P<.01; 1y-postop) and remained at 40.64±2.95D(10y-postop). K2 decreased from 50.57±2.80D to 45.87±2.70D(P<.01; 1y-postop) and remained at 44.00±3.22D(10y-postop).Preoperatively,Kmax was 53.43±2.97D, which showed significant reduction after 10y (44.75±2.14D;P<.01).The IHD decreased from 0.117±0.061 to 0.072±0.038 (1y-postop) and remained to 0.074±0.031(10y-postop).136 eyes showed no further keratoconic progression,while 3-eyes showed progression as documented by corneal topography and 5-eyes noted overcorrection or hyperopic shift,in the 10y follow-up.

Conclusions:

The very long-term results of the Athens Protocol for progressive keratoconus appear to be a safe, effective with little change after the first year in the majority of cases. A small percentage of eyes demonstrated progressive flattening suggesting long-term refractive overcorrection

Financial Disclosure:

-