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Determining the excimer laser ablation rate in the cross-linked (CXL) cornea

Session Details

Session Title: Keratoconus and ectasia

Session Date/Time: Tuesday 08/10/2013 | 16:30-18:00

Paper Time: 17:21

Venue: Elicium 2 (First Floor)

First Author: : O.Richoz SWITZERLAND

Co Author(s): :    S. Arba Mosquera   T. Magnago   F. Hafezi        

Abstract Details

Purpose:

A combination of collagen cross-linking (CXL) and surface ablation, simultaneously or serially, may be a promising means to correct part of the irregular astigmatism in corneal ectasia. Accordingly, surgeons will be confronted with patients that will present with previously cross-linked corneas requiring excimer laser ablation. Currently, the ablation rate per pulse in a cross-linked cornea is unknown.

Setting:

Dept. of Ophthalmology, Geneva University Hospitals, Geneva, Switzerland

Methods:

The laser excimer ablation rate of porcine corneas was analyzed using optical coherence pachymetry (OCP). The following conditions were analyzed: 1) normal cornea, with 5 consecutive ablations of 50 µm each. 2) normal cornea, previously soaked with riboflavin 0.1 %, cross-linked (18mW/cm2), and subjected to 5 consecutive ablations of 50 µm each. 3) normal cornea, previously soaked with riboflavin 0.1 %, cross-linked (3mW/cm2), with 5 consecutive ablations of 50 µm each.

Results:

The following ablation rates were obtained For no CXL: - 1X 50 µm 60 - 2X 50 µm 56 For CXL at 18 mW/cm2: - 1X 50 µm 53 - 2X 50 µm 44 For CXL at 3 mW/cm2: - 1X 50 µm 48 - 2X 50 µm 39

Conclusions:

CXL seems to decrease the ablation rate of the cornea, this decrease seems to be more pronounced in a low fluence CXL (3 mW/cm2)

Financial Interest:

... gains financially from product or procedure presented, ... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, ... is employed by a for-monetary company with an interest in the subject of the presentation