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Mesenchymal stem ?ells in macular and optic nerve degeneration

Session Details

Session Title: Ocular pathologies and training and innovation

Session Date/Time: Monday 07/10/2013 | 08:00-10:00

Paper Time: 09:34

Venue: Emerald (First Floor)

First Author: : P.Beliakouski BELARUS

Co Author(s): :    M. Pazniak   S. Pazniak   M. Kovchel         Sullivan

Abstract Details

Purpose:

To assess the effectiveness of mesenchymal stem cells (MSCs) transplantation in macular degeneration and optic neuropathy treatment.

Setting:

Ophthalmology Department of Tractor Plant Medical Centre, Minsk, Belarus

Methods:

Four eyes of the patients were treated with the transplantation of 3 m autologic MSCs per eye. The injections were performed into subtenon capsules toward the posterior segment of the eyeball and followed by subsequent IV MSCs injections calculated as 1m per 1 kg of body weight. 2 hours before intravenous injection of MSC He-Ne and retinal laser stimulation of fovea centralis were performed. The clinical observation took from four to eight months.

Results:

No reliable changes in OCT data have been registered. There was registered 10-30 per cent (0.1-0.3) increase of visual acuity. In the field of vision there was registered a marked decrease in intensity of central scotoma.

Conclusions:

MSCs autologic transplantation is a safe and effective method in treatment of macular degeneration and optic neuropathy.

Financial Interest:

NONE