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Hydrogel ocular bandages to protect and increase watertight properties of corneal incisions after cataract surgery

Session Details

Session Title: Corneal Incisions and preloaded IOLs

Session Date/Time: Sunday 06/10/2013 | 08:00-09:30

Paper Time: 08:00

Venue: Elicium 2 (First Floor)

First Author: : G.Scaltrini ITALY

Co Author(s): :    M. Piovella              

Abstract Details

Purpose:

To evaluate new liquid hydrogel ocular bandages (OcuSeal and Resure) to cover clear corneal cataract surgical incisions.

Setting:

C.M.A Centro Microchirurgia Ambulatoriale Via Donizetti 24 , Monza (Italy)

Methods:

At the conclusion of cataract surgery, we applied either OcuSeal liquid bandage (Beaver Visitec International) or ReSure Adherent Ocular Bandage (Ocular Therapeutix, Massachusetts, USA) to reinforce closure of clear corneal incisions (up to 3.75 mm). Ocuseal in 242 eyes of 178 patients (87 males, 91 females, mean age 68.36 ± 11.58). Resure in 52 eyes of 49 patients (15 males, 33 females, mean age 67.35 ± 10.22). OcuSeal consists of a synthetic dentritic hydrogel comprised of two separate components: powdered polyethylene glycol (PEG) and liquid polyethylene amine (PEI). The hydrogel is activated upon mixing and is then easily applied as a liquid directly onto the ocular surface. Resure consists of a polyethylene glycol-based hydrogel . The hydrogel is activated by mixing two separate components: powder polyethylene glycol (PEG) and a diluent liquid precursor containing trilysine. After application, both bandages cross-link within 30 seconds to form a smooth, flexible barrier film that protects the incision.

Results:

During the immediate post-operative interval, patients treated with both bandage reported improved comfort. Resure protected the wound by remaining localized over the de-epithelialized tissue for at least 24 hours in 52(100%) of patients while Ocuseal within 12 hours.

Conclusions:

Liquid bandage applied at completion of cataract surgery may enhance incisional wound closure and improves post-operative patient comfort. After refilling with BSS, the anterior chamber is increasing with the bandages due to improvement of watertight properties

Financial Interest:

... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, ... travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented