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Repeatability of corneal layer thickness and vault measures from high resolution optical coherence tomography (OCT)

Session Details

Session Title: Imaging I

Session Date/Time: Sunday 06/10/2013 | 14:30-16:00

Paper Time: 15:44

Venue: Elicium 1 (First Floor)

First Author: : A.Cervińo SPAIN

Co Author(s): :    S. Garcķa-Lįzaro   C. Albarran-Diego   D. Madrid-Costa   F. Pastor     

Abstract Details

Purpose:

To determine the intra- and interobserver repeatability of corneal layer thickness and vault measures determined manually from high resolution anterior segment OCT images.

Setting:

Optometry Research Group Lab

Methods:

Several corneal and phakic IOL images obtained from the HS-100 OCT (Canon Inc, Japan) were analyzed using external image analysis software (ImageJ, NIH, USA). Central thickness of corneal epithelium, Bowman’s layer and stroma were subjectively determined by 5 different experienced observers. Also, central, nasal, and temporal vault measures were obtained from in situ phakic IOL images. Three repeated measures were obtained from each image by each observer.

Results:

Coefficient of variation (COV) was less than 6% for intraobserver repeated measures of all parameters, and less than 9% between observers. Specifically, the best agreement between intraobserver repeated measures was for stromal thickness (0.2%) followed by Bowman’s layer thickness (0.5%), central vault (1,2%), epithelial thickness (3.2%), temporal vault (3.3%) and nasal vault (5,7%). Variation between mean values obtained by the different observers were lower for nasal vault (0.8%), followed by stromal thickness (1.3%), epithelial thickness (1.5%), temporal vault (2.9%), central vault (4.5%) and Bowman’s layer (8.1%)

Conclusions:

Image quality provided by high resolution OCT systems allows repeatable subjective measures of ocular parameters. Differences between observers rely on the subjective interpretation of the boundaries between layers.

Financial Interest:

NONE