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Histopathology results of the open-capsule device for PCO prevention

Session Details

Session Title: PCO

Session Date/Time: Sunday 06/10/2013 | 08:00-09:30

Paper Time: 09:02

Venue: Elicium 1 (First Floor)

First Author: : G.Kleinmann ISRAEL

Co Author(s): :    R. Alon   E. Assia           

Abstract Details

Purpose:

To report the histopathology results of a novel open capsule device to reduce PCO (PID).

Setting:

Harlan Biotec Israel

Methods:

Thirty four New Zealand rabbit eyes were divided into 6 groups after crystalline lens evacuation. Group A: implantation of hydrophilic acrylic IOLs alone, Group B: implantation of hydrophobic acrylic IOLs alone, Group C: implantation of hydrophobic acrylic open capsule devices and hydrophilic acrylic IOLs, Group D: implantation of hydrophobic acrylic open capsule devices and hydrophobic acrylic IOLs, Group E: implantation of hydrophilic acrylic open capsule devices and hydrophilic acrylic IOLs, Group F: implantation of hydrophilic acrylic open capsule devices and hydrophobic acrylic IOLs. The rabbits were followed weekly for 6 weeks. After 6 weeks the rabbits were scarified; the eyes were enucleated and evaluated using the Miyake-Apple view and sent for histological evaluation.

Results:

The PID maintains an open capsule. A 75% decrease in the PCO rates was noticed in the tested groups in comparison with the control groups. An 80% reduction in the Soemmering’s ring formation was noticed in the tested groups in comparison with the control groups. The histopathology demonstrated clear posterior capsule in the tested groups and PCO in the control groups.

Conclusions:

Our results suggested primary PCO prevention by the PID.

Financial Interest:

... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, ... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented