First Author: S.Hsu TAIWAN
Co Author(s): R. Tsai
Purpose:
To measure the disc area and neuroretinal rim in high myopia and analyze the correlations between the measurements with magnification correction and confounders.
Setting:
: Tzu Chi General Hospital and Tzu Chi University, Taiwan
Methods:
This cross-sectional study measured the disc area and neuroretinal rim (rim area and horizontal integrated rim width) in one randomly chosen eye in each of 52 subjects with high myopia using optical coherence tomography (OCT) with magnification correction, and 61 subjects without high myopia as controls. Confounders, such as subject age, spherical equivalent, or axial length, were investigated in highly myopic eyes; and comparisons of the OCT measurements between highly myopic and non-highly myopic eyes were performed.
Results:
In high myopia, the disc area (p=0.954), rim area (p=0.901), and horizontal integrated rim width (p=0.325) did not correlate with subject age. The disc area, rim area, and horizontal integrated rim width negatively correlated with spherical equivalent and positively correlated with axial length in highly myopic eyes (p<0.05). The rim area (p<0.001) and horizontal integrated rim width (p<0.001) both correlated positively with the disc area in high myopia. The disc area (p<0.001), rim area (p<0.001), and horizontal integrated rim width (p<0.001) were significantly larger in highly myopic eyes than in non-highly myopic eyes.
Conclusions:
In highly myopic eyes, neuroretinal rim increases as disc area increases, disc area and neuroretinal rim enlarge as myopia progresses, and disc area or neuroretinal rim are larger than in non-highly myopic eyes.
Financial Disclosure:
No
